Sperm concentration, hyaluronic acid binding capacity, aneuploidy and persistent histones
نویسندگان
چکیده
منابع مشابه
Relation Between Sperm Binding Ability to Hyaluronic Acid With Protamine Deficiency and DNAFragmentation
Purpose: The best sperm selection by its binding ability to hyaluronic acid for ICSI and assessment of correlation between sperm binding ability to hyaluronic acid with sperm parameters, protamine deficiency and DNA fragmentation. Materials and Methods: Semen samples collected from 55 infertile couples referring to ?? Fertility and Infertility center were collected during this study. Semen ana...
متن کاملSperm concentration, hyaluronic acid-binding capacity, aneuploidy and persistent histones in testicular cancer.
STUDY QUESTION Are the quantitative and qualitative characteristics of semen samples of patients with testicular cancer (TC), prior to anticancer therapy, different from infertile oligozoospermic (IO) and normozoospermic (NZ) age-matched men? SUMMARY ANSWER Sperm concentration in TC patients was significantly decreased with no difference in estimated numerical chromosome aberrations and nucle...
متن کاملNo difference in high-magnification morphology and hyaluronic acid binding in the selection of euploid spermatozoa with intact DNA.
In this study, we compared conventional sperm selection with high-magnification morphology based on the motile sperm organellar morphology examination (MSOME) criteria, and hyaluronic acid (HA) binding for sperm chromosome aneuploidy and DNA fragmentation rates. Semen from 50 severe male factor cases was processed through density gradient centrifugation, and subjected to sperm selection by usin...
متن کاملRelationship between Sperm Parameters with Sperm Function Tests in Infertile Men with at Least One Failed Cycle after Intracytoplasmic Sperm Injection Cycle
Objective Imbalance between production of reactive oxygen species (ROS) and total antioxidant capacity in testis, epididymis, and seminal fluid can eventually lead to subfertility and infertility. Abnormal chromatin packaging, and DNA fragmentation is considered as the main underlying causes. In this regard, we aimed to assess relationship between sperm parameters with DNA damage, protamine def...
متن کاملSpermatozoa bound to solid state hyaluronic acid show chromatin structure with high DNA chain integrity: an acridine orange fluorescence study.
During human spermiogenesis, the elongated spermatids undergo a plasma membrane remodeling step that facilitates formation of the zona pellucida and hyaluronic acid (HA) binding sites. Various biochemical sperm markers indicated that human sperm bound to HA exhibit attributes similar to that of zona pellucida-bound sperm, including minimal DNA fragmentation, normal shape, and low frequency of c...
متن کامل